Mouse Kidney Parvovirus testing Now Available!
MKPV was first described in research out of Centenary Institute and was characterised in the paper An Atypical Parvovirus Drives ChronicTubulointerstitial Nephropathy and Kidney Fibrosis. Cell, 2018, 175: 1-14 (Roediger, B et al.) and has since been reported in several animal facilities here in Australia and overseas. MKPV infects both immunocompetent and immunodeficient mice causing inclusions in the renal tubular epithelium and leading to chronic renal disease in middle-aged immunocompromised mice (e.g. Rag-/-, SCID -/- & NSG). MKPV is transmitted to naïve mice by co-housing or dirty bedding transfer and can be detected from numerous samples including serum, faeces, urine, environmental samples and biological material. Contact the lab for more information and advice on how best to incorporate MKPV testing into your Health Monitoring Program.